Scientist
Company: Actalent
Location: Arcadia
Posted on: March 12, 2023
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Job Description:
Description:R & D team is seeking a motivated, collaborative,
and highly skilled Scientist with passion for developing T
cell-based immunotherapies to treat hematologic malignancies and
solid tumors. Candidate is expected to work across the various
aspects of preclinical development and validation of novel T cell /
antibody therapeutics. He / She will work closely with our internal
colleagues and external collaborators to efficiently progress
early-stage cell therapy products through to IND filing. This
position will report directly to the Director of Research &
Development, immunotherapy.The successful candidate has extensive
experience in a combination of skills including, genetic
manipulation of T cells and tumor cells using viral/nonviral
methods, VCN determination using qPCR/ddPCR, T/NK cell isolation,
optimization of culture conditions, immunophenotyping, development
and optimization of a variety of assays (molecular, cell based,
biochemical, immunological) for preclinical validation of cell
therapy products.Lead planning, design, and execution of
experiments related of development and characterization of cellular
immunotherapy products in coordination with R & D director.Analyze,
and report complex data to cross functional teams in a clear and
concise mannerMentor and train scientific staff on technical skills
required to effectively perform experiments and to facilitate
progression of projectsManage multiple research projects
simultaneously with the R & D team and collaborate with other
departments (Process Science, Analytical Science, Quality,
Manufacture) as necessary.Contribute to various preclinical
projects within R& D and those required by clients through in-depth
scientific knowledge and demonstrated experience in analytical
methods used in cellular immunotherapy fieldPerforms a wide range
of non-routine exploratory experiments as requiredMaintain precise
laboratory notebooks, electronic records following high standards
of data quality and integrity.Prepare scientific/technical reports,
summaries, protocols, etc, and present them to internal and
external stakeholders.Constantly improvise research strategies and
adopt technologies to stay upfront in the field of
immunotherapySkills:Clean room, Cell Therapy, batch record review,
LeadTop Skills Details:Clean room, Cell Therapy, batch record
review, LeadAdditional Skills & Qualifications:Antibody
experienceMolecular biology experienceDna manipulation/joining
pieces of dna together (dna cloning)Cell engineering Experience in
phage display library construction, antibody engineering or
affinity maturation of antibodies . 3-4 yearsCell based assay &
mammalian cell culturing Masters + 5 yrs of experience (maybe 2
years is ok if its very specific/ie antibodies it's a very specific
technology)Companies that use this tech (antibodies tech): custom
antibodies companies, Eureka (its in sf)Experience: mammalian cell
culture, antibody & phage display technology, assays, dna, pcrPh. D
in the field of Immunology, Cell biology, Virology or Cancer
biology or related life science discipline with 3+ years
(Scientist) or 5+ years ( Senior Scientist) or Master's degree with
7 + years relevant research experience in Immunology/Cancer
biology. About Actalent: Actalent connects passion with purpose.
Our scalable talent solutions and services capabilities drive value
and results and provide the expertise to help our customers achieve
more. Every day, our experts around the globe are making an impact.
We're supporting critical initiatives in engineering and sciences
that advance how companies serve the world. Actalent promotes
consultant care and engagement through experiences that enable
continuous development. Our people are the difference. Actalent is
an operating company of Allegis Group, the global leader in talent
solutions. The company is an equal opportunity employer and will
consider all applications without regards to race, sex, age, color,
religion, national origin, veteran status, disability, sexual
orientation, gender identity, genetic information or any
characteristic protected by law.
Keywords: Actalent, Arcadia , Scientist, Other , Arcadia, California
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